PENGARUH SALEP EKSTRAK DAUN WIJAYAKUSUMA (Epiphyllum anguliger (Lem.) G.Don) TERHADAP PENYEMBUHAN LUKA SAYAT TIKUS PUTIH (Rattus norvegicus) GALUR SPRAGUE DAWLEY DAN IMPLEMENTASINYA SEBAGAI MEDIA EDUKASI MASYARAKAT

Penulis

  • Rofita Dewi Kartika Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan Universitas Muhammadiyah Surabaya
  • Peni Suharti Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan Universitas Muhammadiyah Surabaya

DOI:

https://doi.org/10.30651/jpb.v5i2.3899

Kata Kunci:

Keywords, Leaf Wijayakusuma (Epiphyllum anguliger (Lem.) G.Don), white rat (Rattus norvegicus) Sprague dawley strain, wound healing

Abstrak

Abstract : The aims of this research are: (1) To know the effect of variation concentration of Wijayakusuma leaf extract (Epiphyllum anguliger (Lem.) G.Don) on duration of wound healing on white rats (Rattus norvegicus) Sprague dawley strain; (2) To implement the result of research into the leaflet as a medium of public education. Quantitative research type with post-test group control design method. Samples in this study of white rat (Rattus norvegicus) Sprague dawley strain 2-3 months old with weight 150-200 grams of 24 tails. While research data of wound healing include morphology of mice skin during wound healing, duration of wound healing and measuring the length of closed wound. The sampling technique uses the RAL technique (Completely Randomized Design). The results showed that: (1) There was an effect of giving ointment with variation of leaf extract concentration of Wijayakusuma to rat wound length in rat significantly; (2) There is effect of giving ointment with variation of Wijayakusuma leaf extract concentration on the duration of wound healing in rat significantly; (3) There is effect of giving ointment with variation of Wijayakusuma leaf extract concentration on healing wound on rat significantly; (4) The most effective ointment in wound healing is an ointment of Wijayakusuma leaf extract with a concentration of 40% with an average duration of wound healing time for ± 7 days; (5) The form of community educational media made from the research is leaflet about ointment leaf extract of Wijayakusuma.

Referensi

Abdurrahmat, A. S.. 2014. Luka, Peradangan, dan Pemulihan. Jurnal Enteropi FMIPA Universitas Negeri Gorontalo. Vol 9 (1) : 721-840.

Biopharmaca Research Center. 2012. Diakses dari: http://biofarmaka.ipb.ac.id/trop-brc-plants-collection/1258-herbal-plants-collection-wijaya-kusuma. February, 23, 2017.

Dandekar, Rucha, dkk. 2015. Evaluation of Anti Inflammatory Activity of Alcohol and Aqueous Extract of Epiphyllum oxypetalum leaves. World Journal of Pharmacy and Pharmaceutical Sciences. Vol 4 (7) : 851-858.

Khaerani, Ulfah. 2013. Bunga Sakti. Jakarta: Dunia Sehat.

Khairany, Noorritha, et al.. 2015. Analisis Sifat Fisik dan Kimia Gel Ekstrak Etanol Daun Talas (Colocasia esculenta (L) Schott). Jurnal FMIPA Universitas Tanjungpura. Vol 4 (2): 81-88.

Mahakam Beta Farma. 2008. Betadine Antiseptic Solution. Diakses dari: http://www.betadine-ina.com/Indonesia/OTC2/Betadine%20Solution.html. February, 22, 2017.

Manikam Pratiwi, Devy. 2015. Induksi dan Identifikasi Senyawa Kalus Sirih Merah (Piper crocatum Ruiz dan Pav) dengan Variasi Konsentrasi 2,4-D dan Kinetin dalam Pelarut Etil Asetat. Skripsi tidak dipublikasikan. Surabaya: Universitas Airlangga.

Qomariah, Siti. 2014. Efektivitas Salep Ekstrak Batang Patah Tulang (Euphorbia tirucalli) pada Penyembuhan Luka Sayat Tikus Putih (Rattus norvegicus). Skripsi dipublikasikan, Semarang: Universitas Negeri Semarang.

R. Dandekar, B. Fegade, VH. Bhaskar. 2015. GC-MS Analysis of Phytoconstituent in Alcohol Extract of Epiphyllum oxypetalumi Leaves. Journal of Pharmacognosy and Phytochemistry. Vol 4 (1) : 148-154.

Robinson, Trevor. 1995. Kandungan Organik Tumbuhan Tinggi Edisi VI. Alih bahasa oleh Kosasih Padmawinata. Bandung: Institut Teknologi Bandung Press.

Upendra, R. S dan Khandelwall, Pratima. 2012. Assesment of Nutritive Values, Phytochemical Constituents and Biotherapeutic Potentials of Epiphyllum oxypetalum. International Journal of Pharmacy and Pharmaceutical Science. Vol 4 (5).

Watson, Roger. 2002. Anatomi dan Fisiologi untuk Perawat Cetakan I. Alih bahasa oleh Sitti Syabariyah. Jakarta: EGC.

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2018-04-05

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