Effectiveness Of Cinnamon (Cinnamomum burmani) And Langsat Leaf (Lansium domesticum) On Reducing Glucose Levels

Authors

  • M Inas Riandi Food Technology Study Program, Mbojo Bima University, Tendean Street, Mande, Mpunda District, Bima Regency, West Nusa Tenggara, 84111

DOI:

https://doi.org/10.30651/pbjppb.v14i2.23714

Keywords:

Indonesia

Abstract

Tradisional plants and spices, including cinnamon and langsat leaves, are easily found in the community and can be used as medicine to control blood sugar levels for people with Diabetes mellitus (DM). This study aimed to determine the level of glucose reduction given a mixture of cinnamon and langsat leaves decoction in vitro. This type of research is a laboratory experiment with a static group comparison research design. The samples will be tested in phytochemical screening and made into a mixture of cinnamon and langsat leaves decoction in a ratio of 20:80, 40:60, 60:40, and 80:20 to see the level of glucose reduction. The results of phytochemical screening on cinnamon showed the presence of flavonoids and saponins, while langsat leaves contained flavonoids, alkaloids, saponins, and phenols. The highest reduction in glucose levels occurred in the concentration variation of 20:80 (20% langsat leaf decoction: 80% cinnamon decoction) with a result of 92.21%. There is an effect between variations in the concentration of langsat leaves and cinnamon decoction water on reducing glucose levels in vitro.

References

Abd Sukri, S. M., Ramadhani, N., Larassati, E., & Septiandi, B. H. H. (2023). Determination Of Paracetamol Levels Using The Uv-Vis Spectrophotometry Method. Asian Journal of Analytical Chemistry, 1(2), 51-57.

Al-Ishaq, R. K., Abotaleb, M., Kubatka, P., Kajo, K., & Büsselberg, D. (2019). Flavonoids and their anti-diabetic effects: Cellular mechanisms and effects to improve blood sugar levels. Biomolecules, 9(9), 430.

Al-kayyis, H. K., & Susanti, H. (2016). Perbandingan metode somogyi-nelson dan anthrone-sulfat pada penetapan kadar gula pereduksi dalam umbi cilembu (Ipomea batatas L.). Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community), 13(2), 81-89.

Anggriawan, Made B., Roswiem, Anna P.,Waras N. Potensi Ekstrak Air Dan Etanol Kulit Batang Kayu Manis Padang (Cinnamomum Burmanii) Terhadap Aktivitas Enzim A-Glukosidase. Jurnal Kedokteran YARSI, vol. 23, no. 2, Aug. 2015, pp. 91-102, doi:10.33476/jky.v23i2.114.

Awaluddin, A., Syarifah, A., & Aslina, A. (2021). Pengaruh Rebusan Kayu Manis Terhadap Kadar Gula Darah Pasien Diabetes Mellitus Tipe II. Ensiklopedia of Journal, 3(4), 135-140.

Derek, Meivy I., Julia Rottie, and Vandri Kallo. (2017). Hubungan tingkat stres dengan kadar gula darah pada pasien diabetes melitus tipe II di Rumah sakit pancaran kasih GMIM Manado." Jurnal Keperawatan 5(1). 1-6.

Fiana, N., & Oktaria, D. (2016). Pengaruh kandungan saponin dalam daging buah mahkota dewa (Phaleria macrocarpa) terhadap penurunan kadar glukosa darah. Jurnal Majority, 5(4), 128-132.

Lantah, P. L., Montolalu, L. A., & Reo, A. R. (2017). Kandungan fitokimia dan aktivitas antioksidan ekstrak metanol rumput laut Kappaphycus alvarezii. Media Teknologi Hasil Perikanan, 5(3), 73-79.

Maula, N. N. M., Mustika, R. A., Wahyuni, S., & Faizah, U. N. (2023, December). Potential Antioxidant Compounds Contained in Secang Wood (Caesalpinia sappan L) for Natural Skin Care. In PISCES: Proceeding of Integrative Science Education Seminar (Vol. 3, No. 1, pp. 65-71).

Mohsin, S. N., Saleem, F., Humayun, A., Tanweer, A., & Muddassir, A. (2023). Prospective Nutraceutical Effects of Cinnamon Derivatives Against Insulin Resistance in Type II Diabetes Mellitus—Evidence From the Literature. Dose-Response, 21(3), 15593258231200527.

Munthe, R. M. I. (2021). Potensi Kayu Manis sebagai Antidiabetik. Jurnal Penelitian Perawat Profesional, 3(2), 303-310.

Nainggolan, M., Ahmad, S., Pertiwi, D., & Nugraha, S. E. (2019). Penuntun dan Laporan Praktikum Fitokimia. Medan Univ Sumatra Utara.

Narsih, N., & Agato, A. (2018). Efek kombinasi suhu dan waktu ekstraksi terhadap komponen senyawa ekstrak kulit lidah buaya. Jurnal Galung Tropika, 7(1), 75-87.

Nazareno, A. M., Purnamasari, L., & dela Cruz, J. F. (2022). In vivo and In vitro anti-diabetic effects of cinnamon (Cinnamomum sp.) plant extract: A review. Canrea Journal: Food Technology, Nutritions, and Culinary Journal, 151-171.

Onggirawan, Felicia. (2014) Efek Ekstrak Etanol Kayu Manis (Cinnamomum burmannii) Terhadap Penurunan Kadar Glukosa Darah. Undergraduate thesis, Universitas Kristen Maranatha.

Panche, A. N., Diwan, A. D., & Chandra, S. R. (2016). Flavonoids: an overview. Journal of nutritional science, 5, e47.

Parwata, A., Dina, M. N., & Yasa, S. (2018). The contents of phenol and flavonoid compounds in water extract of Gyrinops versteegii leaves have potentially as natural antioxidants and hypoglicemic in hyperglycemic Wistar rats. Biomedical and Pharmacology Journal, 11(3), 1543-1553.

Ridho, F. M. (2023). Mechanism of Alkaloids and Flavonoids in Bajakah (Uncaria nervosa Elmer) as Antidiabetic Agents. Jurnal Ilmu Medis Indonesia, 3(1), 9-16.

Roep, B. O., Thomaidou, S., van Tienhoven, R., & Zaldumbide, A. (2021). Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?). Nature Reviews Endocrinology, 17(3), 150-161.

Russo, B., Picconi, F., Malandrucco, I., & Frontoni, S. (2019). Flavonoids and insulin-resistance: from molecular evidences to clinical trials. International journal of molecular sciences, 20(9), 2061.

Shalihah, H. (2022). Perbandingan Efektivitas Infusa Dan Rebusan Daun Langsat (Lansium domesticum L) Dalam Menurunkan Kadar Glukosa Secara In Vitro. Klinikal Sains: Jurnal Analis Kesehatan, 10(1), 53-61.

Sofihidayati, T., Wardatun, S., & Suraya, A. (2021). Perbandingan Kadar Flavonoid Serbuk Instan Kunyit Putih (Curcuma Zedoaria Rosc.) Yang Beredar Di Pasaran Dengan Metode Spektrofotometri UV-VIS. Jurnal Sosial dan Sains, 1(12), 1-614.

Sufiana, H. (2014). Uji Aktivitas Antioksidan Dan Sitotoksisitas Campuranekstrak Metanol Kayu Sepang (Caesalpinia sappan L.) dan Kulit Kayu Manis (Cinnamomum burmannii B.). Jurnal Kimia Khatulistiwa, 3(2).

Sukmawati, S. (2018). Optimasi dan Validasi Metode Analisis dalam Penentuan Kandungan Total Flavonoid pada Ekstrak Daun Gedi Hijau (Abelmoscus manihot L.) yang Diukur Menggunakan Spektrofotometer UV-Vis. PHARMACON, 7(3).

Suprijono, A., Kusumaningrum, D. A., & Kusmita, L. (2018). Pengaruh pemberian ekstrak etanol dan isolat flavonoid teh oolong (Camellia sinensis [L.] O. K) terhadap penurunan kadar glukosa secara in vitro. In Prosiding Seminar Nasional Unimus (Vol. 1).

Wardatun, S., Yulia, I., & Aprizayansyah, A. (2016). Kandungan flavonoid ekstrak metanol dan ekstrak etil asetat daun sukun (artocarpus altilis (park.) fosberg) dan aktivitasnya terhadap penurunan kadar glukosa secara in vitro. FITOFARMAKA: Jurnal Ilmiah Farmasi, 6(2), 52-63

Published

2026-10-31

Issue

Section

Artikel