Prominent bradycardia in a COVID-19 patient receiving Remdesivir: a case report

Sidhi Laksono Purwowiyoto (1), Grace Trifena Hosea (2)
(1) Fakultas Kedokteran Universitas Muhammadiyah Prof Dr Hamka, Indonesia,


Remdesivir is a commonly used antiviral drug to treat COVID-19. Remdesivir has some side effects; however, whether it has any effect on cardiac is rarely reported. A 44-year-old woman with symptomatic confirmed COVID-19 was treated with intravenous remdesivir 200 mg on day one and followed with 100 mg remdesivir until day five. Three days after the treatment, she had significant bradycardia shown on the electrocardiography; however, the patient had no complaint or symptom regarding the bradycardia. Based on the discussion with the cardiology team, it was decided to cease remdesivir and replace it with oseltamivir, and the ECG showed some improvement. Remdesivir is a drug that should be used safely and cannot be taken at home, as there may be side effects left unaware. 

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Sidhi Laksono Purwowiyoto (Primary Contact)
Grace Trifena Hosea
Author Biography

Sidhi Laksono Purwowiyoto, Fakultas Kedokteran Universitas Muhammadiyah Prof Dr Hamka

Kepala Laboratorium Kateterisasi Jantung KSM Jantung RSUD Pasar Rebo, Jakarta Timur

Purwowiyoto, S. L., & Hosea, G. T. (2022). Prominent bradycardia in a COVID-19 patient receiving Remdesivir: a case report. Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya, 6(2).

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