Deteksi Dini dan Manajemen Awal Penyakit Jantung Bawaan Kritis
Abstrak
Critical congenital heart disease (CCHD) represents a severe subset of congenital heart defects (CHD) with high neonatal mortality rates if undiagnosed or untreated. This review highlights the prevalence, diagnosis, and management strategies for CCHD. In Asia, CHD prevalence is among the highest globally, contributing significantly to neonatal mortality. Early detection, such as prenatal ultrasound and pulse oximetry screening, plays a crucial role in improving patient outcomes. While fetal echocardiography provides diagnostic insights, it has limitations, emphasizing the value of postnatal pulse oximetry as a cost-effective, non-invasive screening tool. Management involves early interventions, including hemodynamic stabilization, pharmacological therapies like prostaglandin infusion, and surgical or catheter-based procedures. Definitive corrective surgeries, although complex, are increasingly performed in neonates to minimize long-term complications. Early diagnosis and timely referral to advanced facilities remain vital to reducing mortality and enhancing the quality of life for affected neonates.
Artikel teks lengkap
Referensi
Akkinapally, S., Hundalani, S. G., Kulkarni, M., Fernandes, C. J., Cabrera, A. G., Shivanna, B., & Pammi, M. (2018). Prostaglandin E1 for maintaining ductal patency in neonates with ductal-dependent cardiac lesions. In Cochrane Database of Systematic Reviews (Vol. 2018, Issue 2). John Wiley and Sons Ltd. https://doi.org/10.1002/14651858.CD011417.pub2
Cucerea, M., Simon, M., Moldovan, E., Ungureanu, M., Marian, R., & Suciu, L. (2016). Congenital Heart Disease Requiring Maintenance of Ductus Arteriosus in Critically Ill Newborns Admitted at A Tertiary Neonatal Intensive Care Unit. J. Crit. Care Med., 2(4), 185–191. https://doi.org/10.1515/jccm-2016-0031
Engel, M. S., Kochilas, L. K., & Engel, M. (2016). Pulse oximetry screening: a review of diagnosing critical congenital heart disease in newborns. https://doi.org/10.2147/MDER.S102146
Khamkar, A. M., Pote, P. D., & Jose, G. E. (2022). A Comparison of Finger Pulse Oximeter and SET-Based Neonatal Pulse Oximeter in Neonates in Terms of SpO2 Values and Response Time. Indian J. of Pediatr. https://doi.org/10.1007/s12098-022-04274-1
Kemenkes Ri. (2023). Modul Pelatihan Dasar Skrining Bayi Baru Lahir Bagi Dokter, Bidan dan Perawat di Puskesmas. Direktoral Jendral Peningkatan MutuTenaga Kesehatan,13-14
Kim, S. H. (2017). Recent advances in pediatric interventional cardiology. In Korean J. of Pediatr. (Vol. 60, Issue 8, pp. 237–244). Korean Pediatric Society. https://doi.org/10.3345/kjp.2017.60.8.237.
Kondo, M., Ohishi, A., Baba, T., Fujita, T., & Iijima, S. (2018). Can echocardiographic screening in the early days of life detect critical congenital heart disease among apparently healthy newborns? BMC Pediatr., 18(1). https://doi.org/10.1186/s12887-018-1344-z.
Murni, I. K., Wibowo, T., Arafuri, N., Oktaria, V., Dinarti, L. K., Panditatwa, D., Patmasari, L., Noormanto, N., & Nugroho, S. (2022). Feasibility of screening for critical congenital heart disease using pulse oximetry in Indonesia. BMC Pediatr, 22(1). https://doi.org/10.1186/s12887-022-03404-0
Nastiti, P. H., Handayani, K. D., Hidayat, T., Angelika, D., Utamayasa, I. K. A., Etika, R., Rachman, M. A., & Utomo, M. T. (2023). Intermittent pulse oximeter as a measurement of newborn oxygen: a cross-sectional study. Bali Med. J., 12(3), 2446–2450. https://doi.org/10.15562/bmj.v12i3.4688
Plana, M. N., Zamora, J., Suresh, G., Fernandez-Pineda, L., Thangaratinam, S., & Ewer, A. K. (2018). Pulse oximetry screening for critical congenital heart defects. In Cochrane Database of Systematic Reviews (Vol. 2018, Issue 3). John Wiley and Sons Ltd. https://doi.org/10.1002/14651858.CD011912.pub2.
van Vliet, J. T., Majani, N. G., Chillo, P., & Slieker, M. G. (2024). Diagnostic Accuracy of Physical Examination and Pulse Oximetry for Critical Congenital Cardiac Disease Screening in Newborns. In Children (Vol. 11, Issue 1). Multidisciplinary Digital Publishing Institute (MDPI). https://doi.org/10.3390/children11010047.
Wang, D., Fang, J., Sun, D., Xia, K., Liu, N., Liu, Q., & Zhang, Y. (2021). Original Article Improvement of cardiac function in children with congenital heart disease (involving a left-to-right shunt) treated with angiotensin-converting enzyme inhibitor captopril. In Int J Clin Exp Med (Vol. 14, Issue 1). www.ijcem.com/.
Penulis
Hak Cipta (c) 2025 Mahrus Abdur Rahman
Artikel ini berlisensi Creative Commons Attribution 4.0 International License.
Qanun Medika oleh FK UM Surabaya disebarluaskan di bawah Lisensi Creative Commons Atribusi 4.0 Internasional.
Berdasarkan ciptaan pada http://journal.um-surabaya.ac.id/index.php/qanunmedika.