Understanding Pacing-Induced Cardiomyopathy: a mini review

Sidhi Laksono Purwowiyoto (1), Reynaldo Halomoan Siregar (2), Steven Philip Surya (3)
(1) Faculty of medicine of Universitas Muhammadiyah Prof Dr Hamka, Indonesia,
(2) Faculty of medicine of Atma Jaya Catholic University, Indonesia,
(3) Army Hospital Kesdam Cijantung


Patients with total atrioventricular block or sinus node dysfunction will need pacemaker implantation to improve the physiologic function of the heart.  It is known that chronic pacing such as right ventricular pacing could deteriorate the cardiac function (decreased left ventricular ejection fraction) due to dyssynchrony. This condition is knows as pacing-induced cardiomyopathy (PICM). The incidence of PICM could reach 19.5% during 3 years follow-up. The right ventricle is one of the locations for implantation. Chronic right ventricular pacing may cause interventricular dyssynchrony and disrupt the contraction mechanism in the heart. These will lead to cardiac remodeling and eventually impair the left ventricular function. Therapy is needed in patients with PICM to improve the symptoms and maintain the cardiac function. This article will further highlight the definition, mechanism, risk factor, treatment and preventive strategy for patients with PICM.

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Sidhi Laksono Purwowiyoto
sidhilaksono@uhamka.ac.id (Primary Contact)
Reynaldo Halomoan Siregar
Steven Philip Surya
Author Biography

Sidhi Laksono Purwowiyoto, Faculty of medicine of Universitas Muhammadiyah Prof Dr Hamka

Head of cardiac catheterization laboratory, Department of cardiology and vascular medicine, RSUD Pasar Rebo, East Jakarta

Purwowiyoto, S. L., Siregar, R. H., & Surya, S. P. (2021). Understanding Pacing-Induced Cardiomyopathy: a mini review. Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya, 5(2). https://doi.org/10.30651/jqm.v5i2.6036

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