Hubungan Gula Darah, Asam Urat dan Hemoglobin dengan Tekanan Darah Lansia
The Relationship between Blood Sugar, Uric Acid, and Hemoglobin with Blood Pressure in the Elderly
DOI:
https://doi.org/10.30651/jkm.v10i4.29324Keywords:
Blood Sugar, Uric Acid, Hemoglobin, Blood Pressure, ElderlyAbstract
Objective: Hypertension is a leading cause of death worldwide, with over one billion people suffering from it. Several factors influence blood pressure, including blood sugar, uric acid, and hemoglobin. This study aimed to analyze the relationship between blood sugar, uric acid, and hemoglobin with blood pressure.
Methods: The study design was correlational with a cross-sectional approach. The study population was 46 elderly people in Puton Village, Diwek District, Jombang Regency. Data on uric acid, blood sugar, and hemoglobin levels were collected using a multifunction blood test device through peripheral blood sampling. Blood pressure was measured using a sphygmomanometer according to standard guidelines. Data were analyzed using coding, editing, tabulation, and scoring, and statistical tests were performed using the Spearman Rank test.
Results: Most respondents (73.9%) had high blood sugar. Most respondents (71.7%) had high uric acid (33%). Half of respondents (50%) had normal hemoglobin (23%). Nearly half of respondents (34%) had prehypertensive systolic blood pressure and stage 1 hypertension (34.8%) each. Half of the respondents had diastolic blood pressure (50%, 23 people) with grade 1 hypertension. The Spearman rank test for blood sugar and uric acid levels on systolic and diastolic blood pressure using SPSS yielded a p value > 0.05, indicating no correlation. The correlation between hemoglobin and diastolic blood pressure yielded a p value > 0.05, indicating no correlation. The hemoglobin-systolic blood pressure test yielded a p value of 0.017, less than 0.05, with a correlation coefficient of 0.349, indicating a moderate correlation between hemoglobin and systolic blood pressure.
Conclusion: Proper control of the intervening variables is essential to ensure a truly homogeneous sample of respondents to achieve optimal results. The number of respondents should be increased.
References
American Diabetes Association. (2022). Standards of Medical Care in Diabetes 2022. ADA.
Badura, K., Janc, J., Wąsik, J., Gnitecki, S., Skwira, S., Młynarska, E., Rysz, J., & Franczyk, B. (2024). Anemia of chronic kidney Disease—A narrative review of its pathophysiology, diagnosis, and management.Biomedicines,12(6), 1191.
Chen, Y., Wang, T., & Li, X. (2021). Fasting glucose levels and blood pressure among non-diabetic adults: A cross-sectional analysis. Journal of Clinical Hypertension, 23(4), 677–684.
Cui, L., Li, Z., & Wang, Y. (2021). Uric acid levels and hypertension: The role of metabolic syndrome. Journal of Clinical Hypertension, 23(9), 1682–1690.
Dekker, J. M., Peters, R., & de Jong, P. (2020). Hemoglobin concentration and blood pressure: Evidence from population studies. Hypertension Research, 43, 541–548.
Dinas Kesehatan Kabupaten Jombang. (2019). Profil Kesehatan Kabupaten Jombang 2019.
Dinas Kesehatan Provinsi Jawa Timur. (2020). Profil Kesehatan Provinsi Jawa Timur 2020. Dinas Kesehatan Provinsi Jawa Timur. www.dinkesjatimprov.go.id
Ezwaie, M., Ezwaie, R., Younis, S., & Elfigih, S. (2024). Prevalence and risk factors of erythropoiesis stimulating agents hyporesponsiveness in chronic hemodialysis patients attending nephrology center of Benghazi.Libyan Journal of Medical Research,18, 112-28.
Feig, D. I., & Johnson, R. J. (2021). Hyperuricemia and hypertension: Mechanisms and clinical implications. Nature Reviews Nephrology, 17, 746–760.
Fishbane S, Coyne DW (2020). How I treat renal anemia. Blood.;136(7):783-789.;
Fishbane, S. (2021). Anemia management: a historical perspective. In Kidney International Supplements(Vol. 11, Issue 1, pp. 3–7). Elsevier B.V.
Huang, Z., Chen, X., & Li, M. (2020). Factors associated with blood pressure variability: A population-based study. Journal of Human Hypertension, 34, 789–797.
Jonaitienė, N., Ramantauskaitė, G., & Laukaitienė, J. (2021). Anaemia in heart failure patients, associated with angiotensin–renin–aldosterone system altering medications.Heart Views,22(3), 196-200.
Kementerian Kesehatan RI. (2019). Infodatin Hipertensi Si Pembunuh Senyap.
Kim, S. Y., Kang, M., & Park, J. (2020). Uric acid and hypertension: The role of metabolic factors. BMC Cardiovascular Disorders, 20, 256.
Komang, Ayu Kumalasari and Cokorda, Dewi Widhya Hana Sundari and Burhannuddin, Burhannuddin (2020). Hubungan Kadar Asam Urat Dengan Kejadian Hipertensi Pada Lansia Di Wilayah Kerja UPT Kesmas Sukawati I. https://repository.poltekkes-denpasar.ac.id/5567/.
Lisi, F., Parisi, G., Gioia, M. I., Amato, L., Bellino, M. C., Grande, D., Massari, F., Caldarola, P., Ciccone, M. M., & Iacoviello, M. (2020). Mineralcorticoid receptor antagonist withdrawal for hyperkalemia and mortality in patients with heart failure.Cardiorenal Medicine,10(3), 145-153.
Liu, Y., Sun, H., & Zhao, R. (2023). Chronic hyperglycemia and endothelial dysfunction in the development of hypertension. Cardiovascular Diabetology, 22, 114.
Luo, D., Zhang, Q., & Lin, J. (2023). Hemoglobin levels and blood pressure in adults: A systematic review. BMC Public Health, 23, 1124.
Maiuolo, J., Oppedisano, F., & Muscoli, C. (2020). Uric acid: An old molecule with new functions. Nutrients, 12(11), 3141.
Nugroho, A., & Lestari, D. (2022). Hubungan kadar glukosa darah dengan tekanan darah pada dewasa sehat. Jurnal Kesehatan Masyarakat Indonesia, 18(1), 45–52.
Patel, K., Singh, P., & Kumar, R. (2021). Effects of hematological parameters on systemic blood pressure. Journal of Human Hypertension, 35, 699–706.
Praningsih S, Maryati H, Siswati S. (2020). Surveillance Hipertensi Kader "Ceria" Dalam Upaya Pencegahan Kecacatan Dan Kematian. Journals of Ners Community, 228-235
Roniawan HF, Octaviani P, Prabandari R, (2021). Hubungan Kadar Gula Darah Dengan Tekanan Darah Pasien Diabetes Melitus Tipe 2 Di Puskesmas Sokaraja 1. https://www.journal.stifera.ac.id/index.php/jfsi. Volume 4 nomor 2,Oktober 2021.
Saeed, M. K., Ho, V., & Erickson, K. F. (2020). Consolidation in dialysis markets—causes, consequences, and the role of policy. InSeminars in dialysis(Vol. 33, No. 1, pp. 90-99).
Siswati S, dkk. (2021). Senam Hipertensi Sebagai Upaya Menurunkan Tekanan Darah Pada Penderita Hipertensi. 6(2). 46–50. DOI: https://doi.org/10.24929/jik.v6i2.1504
Toyoda, K., Yoshimura, S., Fukuda-Doi, M., Qureshi, A. I., Inoue, M., Miwa, K., & Koga, M. (2023). Intravenous nicardipine for Japanese patients with acute intracerebral hemorrhage: an individual participant data analysis.Hypertension Research,46(1), 75-83.
Wang, J., Xu, F., & Chen, Y. (2021). Variability of random glucose levels and its clinical implications: A cross-sectional study. Primary Care Diabetes, 15(3), 512–519.
WHO. (2021a). Guideline for the pharmacological treatment of hypertension in adults. https://www.who.int/publications/i/item/9789240033986
WHO. (2021b). Hypertension. WHO. https://www.who.int/health-topics/ hypertension #tab=tab_1
Wu, H., Cheng, H., Wang, C., Yao, L., Qin, S., Zuo, L., Hu, Z., Zhang, C., Wu, Y., Hofherr, A., Mohan, K., Rush, S., & Li, X. (2024). Roxadustat and Oral Iron Absorption in Chinese Patients with Anemia of Chronic Kidney Disease: A Randomized, Open-Label, Phase 4 Study (ALTAI). Advances in Therapy, 41(3), 1168–1183.
Young, E. W., Wang, D., Kapke, A., Pearson, J., Turenne, M., Robinson, B. M., & Huff, E. D. (2023). Hemoglobin and Clinical Outcomes in Hemodialysis: An Analysis of US Medicare Data From 2018 to 2020. Kidney Medicine, 5(2), 100578.
Zhang, H., Liu, B., & Chen, Z. (2022). Hemoglobin and systolic blood pressure: A population-based study. Scientific Reports, 12, 8812.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Supriliyah Praningsih, Heni Maryati, Fitri Firranda F, Heni Maryati, Eka Mei Dianita, Pepin Nahariani

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
- Penulis tetap memegang hak atas karyanya dan memberikan hak publikasi pertama kepada jurnal ini yang secara simultan karya tersebut dilisensikan di bawah:Â Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0)







