Cardio-vocal Syndrome as a Complication Patient with Severe Mitral Regurgitation and Moderate Aortic Regurgitation with Pulmonary Hypertension
Abstract
ABSTRACT
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Hoarseness due to paralysis of vocal cord, as in Cardio-vocal syndrome, is caused by mechanical affection of left recurrent laryngeal nerve from enlarged cardiovascular structures. Mitral valve prolapse is rarely found to cause this syndrome. Case report presenting a 47 years old male visited the outpatient department with a clinical history of dyspnea and hoarseness since a year ago. Physical examination revealed late systolic murmur in apex and low-grade diastolic murmur in right second intercostal space. Echocardiography confirmed severe mitral regurgitation due to flail anterior mitral valve leaflet with severe left atrium dilatation (9.0 cm) and moderate aortic regurgitation due to mal-coaptation of aortic valves. Laryngoscopy revealed an immobile left vocal cord. He underwent successful double valve replacement after three months follow up the patient showed improvement of hoarseness. The incidence of Cardio-vocal syndrome in mitral valve disease varies from 0.6% to 5%. In cases diagnosed with thoracic disease, paralysis of the left vocal cord was reported 1.75 times more frequent than the right side. The aim of this case report is we have to aware that Cardio-vocal syndrome is a rare cause of vocal cord paralysis and should be considered as a differential diagnosis of hoarseness, particularly if the patient has a cardiac history. Comprehensive evaluation and prompt treatment may allow reversal of the damage to left recurrent laryngeal nerve. Permanent nerve damage can occur due to late diagnosis.
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Keywords            : Cardio-vocal syndrome, Mitral regurgitation, Aortic Regurgitation
Correspondence  : adityobasworo@gmail.com
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References
Acharya, M. N., Bahrami, T., Popov, A. F., & Bhudia, S. K. (2017). Rapid resolution of Ortner’s syndrome with giant left atrium after double-valve replacement surgery. Interactive Cardiovascular and Thoracic Surgery, 25(4), 663–664. https://doi.org/10.1093/icvts/ivx166
Anuar, K., Baki, M. M., Sani, A., & Sabir Husin Athar, P. P. (2011). Hoarseness Due to Cardiovascular Disease: Two Cases of Cardiovocal Syndrome. Philippine Journal of Otolaryngology-Head and Neck Surgery, 26(2), 31–33. https://doi.org/10.32412/pjohns.v26i2.579
Baumgartner, H., Falk, V., Bax, J. J., Hamm, C., Holm, P. J., Lancelotti, P., & Lansac, E. (2017). 2017 ESC / EACTS Guidelines for the management of valvular heart disease The Task Force for the Management of Valvular Heart Disease. European Heart Journal, (38), 2739–2791. https://doi.org/10.1093/eurheartj/ehx391
Chen, R. F., Lin, C. T., & Lu, C. H. (2009). Ortner’s syndrome - A rare cause of unilateral vocal cord paralysis: A case report. Kaohsiung Journal of Medical Sciences, 25(4), 203–206. https://doi.org/10.1016/S1607-551X(09)70061-0
Kaipuzha, R. R., Pulimootti, D. T., Bakshi, S. S., & Gopalakrishnan, S. (2018). Ortner’s Syndrome: Looking Back at this Rarity. Journal of Clinical and Preventive Cardiology, (7), 168–170. https://doi.org/10.4103/JCPC.JCPC
Kishan, C. V., Wongpraparut, N., Adeleke, K., Frechie, P., & Kotler, M. N. (2000). Ortner’s syndrome in association with mitral valve prolapse. Clinical Cardiology, 23(4), 295–297. https://doi.org/10.1002/clc.4960230416
Loughran, S., Alves, C., & MacGregor, F. B. (2002). Current aetiology of unilateral vocal fold paralysis in a teaching hospital in the West of Scotland. Journal of Laryngology and Otology, 116(11), 907–910. https://doi.org/10.1258/00222150260369426
Mulpuru, S. K., Vasavada, B. C., Punukollu, G. K., & Patel, A. G. (2008). Cardiovocal Syndrome: A Systematic Review. Heart Lung and Circulation, 17(1), 1–4. https://doi.org/10.1016/j.hlc.2007.04.007
Plastiras, S. C., Pamboucas, C., Zafiriou, T., Lazaris, N., & Toumanidis, S. (2010). Ortner’s syndrome: A multifactorial cardiovocal syndrome. Clinical Cardiology, 33(6), 2009–2010. https://doi.org/10.1002/clc.20646
Ramasamy, P., Kale, S. B., Ramalingam, S., & Veerappa, M. (2018). A rare cause for aphonia - Ortners syndrome. International Journal of Otorhinolaryngology and Head and Neck Surgery, 4(5), 1321. https://doi.org/10.18203/issn.2454-5929.ijohns20183710
Seyed Toutounchi, S. J., Eydi, M., Golzari, S. E., Ghaffari, M. R., & Parvizian, N. (2014). Vocal cord paralysis and its etiologies: a prospective study. Journal of Cardiovascular and Thoracic Research, 6(1), 47–50. https://doi.org/10.5681/jcvtr.2014.009
Stocker, H., & Enterline, H. T. (1958). “Cardio-Vocal Syndromeâ€: Laryngeal Paralysis in Intrinsic Heart Disease. American Heart Journal, 56(1), 51–59. https://doi.org/https://doi.org/10.1016/0002-8703(58)90158-3
Sunderland, S. S. (1990). The anatomy and physiology of nerve injury. Muscle & Nerve, 13(9), 771–784. https://doi.org/https://doi.org/10.1002/mus.880130903
Tammiraju, I., Krishna, T. R., Prasad, P. V., & Babu, K. J. (2018). Ortner’s syndrome (Cardio Vocal Hoarseness) – A rare entity in modern era. A case report. IHJ Cardiovascular Case Reports (CVCR), 2(2), 82–84. https://doi.org/10.1016/j.ihjccr.2018.02.006
Wu, V. C. C., Chen, C. C., Hung, K. C., Chern, M. S., Wan, Y. L., Tsai, F. C., & Lin, F. C. (2013). Reversal of hoarseness with recognition of Ortner syndrome in a patient with severe mitral regurgitation. Journal of Cardiology Cases, 7(2), e48–e50. https://doi.org/10.1016/j.jccase.2012.10.009
Yuan, S. (2014). Ortner ( Cardio-vocal ) Syndrome : A Collective Review. Kuwait Medical Journal, (46), 3–13.
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