Bilah Samping Artikel

Telah diserahkan
Februari 10, 2023
Diterima
Mei 30, 2023
Diterbitkan
Mei 30, 2023
Unduh
PDF
Statistik
Baca Penghitung : 299 Unduh : 499

Isi Artikel Utama

Abstrak

Chronic diabetes mellitus is carried on by a rise in blood glucose levels as a result of decreased insulin sensitivity to manage blood sugar levels. The purpose of this study was to analyze participants with controlled and uncontrolled type 2 diabetes in relation of blood glucose, insulin, Homa-IR, and SCUBE2 protein levels. This study has a cross-sectional design and is descriptive analytic research. The sample for this study was stored biological fluid which was collected by total sampling from the Roemani Muhammadiyah Hospital Semarang Laboratory Installation in September 2022 to October 2022. The T-Independent test and the Mann-Whitney U-test used to the data analysis. The results of the T-Independent test results suggest that there was no significant variance between the insulin levels in DMT2 patients who were in control and those who unable (p=0.820, p>0.05). According to the results of the Mann-Whitney U-test analysis, there was no significant difference in the levels of scube2 protein between controlled and uncontrolled T2DM, and there was a significant difference in the glucose levels and Homa-IR values between controlled and uncontrolled T2DM, including both.but there was a significant effect of differences in glucose levels and Homa-IR values. The conclusion is that there are differences in glucose levels and Homa-IR values in controlled and uncontrolled DMT2 and there is no difference in insulin and scube 2 protein levels in controlled and uncontrolled DMT2.

 

 

Keywords: Glucose, Insulin, Homa-IR, Protein Scube2

Rincian Artikel

Lisensi

 

This work is licensed under  Creative Commons Attribution-NonCommercial 4.0 International License.

 

Biografi Penulis

Nisa Julia Safarti, Universitas Muhammadiyah Semarang

Magister Laboratorium Klinis/Medis

Budi - Santosa, Universitas Muhammadiyah Semarang

Magister Ilmu Laboratorium Klinis, Lektor Kepala

Referensi

  1. Merentek, E. (2006). “Resistensi Insulin Pada Diabetes Melitus Tipe 2. Cermin Dunia Kedokteran, 150, 38-41.â€
  2. Nababan, Poltak. 2019. “Hubungan Kadar TNF-α Dengan HOMA-IR Pada Pasien Diabetes Mellitus Tipe-2 Di Rumah Sakit.†10(3): 580–83.
  3. Oroh, Wenda. 2018. “Hubungan Obesitas Dengan Kejadian Diabetes Melitus Di Wilayah Kerja Puskesmas Ranomut Kota Manado.†Jurnal Keperawatan 6(1): 1–6.
  4. Restyana, Fatimah. 2015. “Restyana Noor Fatimah.†Diabetes Melitus Tipe 2 4(5): 1–12. http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1061.
  5. Sekaran et al. 2018. “Pemeriksaan Kadar HbA1c Pada Penderita Diabetes Mellitus Tipe 2 Yang Di Rawat Jalan Di Rsup h. Adam Malik Medan.†Pakistan Research Journal of Management Sciences 7(5): 1–2.
  6. Sianturi, David. 2021. “Korelasi Rasio Proinsulin / Insulin Dengan Reseptor Adiponektin Setelah Pemberian Ektrak Daun Puguntano (Curanga Fel-TerraeMerr.) Pada Tikus Putih Galur Wistar Model Diabetes Mellitus Tipe 2.†Jurnal Pembangunan Wilayah & Kota 1(3): 82–91.
  7. Soelistijo Sa, Hermina Novida, Rudijanto A, Soewondo P, Suastika K, Manaf A. 2015. Pengelolaan Dan Pencegahan Diabetes Melitus Tipe 2 Di Indonesia 2015.
  8. Suiraoka, I. P. 2012. “Penyakit Degeneratif. Yogyakarta Nuha Medika, 45-51.†: 45–51.
  9. Tsalissavrina, Iva, Kanthi Permaningtyas Tritisari, Dian Handayani, and Inggita Kusumastuty. 2018. “Hubungan Lama Terdiagnosa Diabetes Dan Kadar Glukosa Darah Dengan Fungsi Kognitif Penderita Diabetes Tipe 2 Di Jawa Timur.†Jurnal AcTion 3(1): 28–33.
  10. Utara, Universitas Sumatera. 2016. “Hubungan Resistensi Insulin Menggunakan Homa-Ir Dengan Rasio Profil Lipid Pada Penderita Sindroma Metabolik.†FAKULTAS KEDOKTERAN UNIVERSITAS SUMATRA UTARA.
  11. Merentek, E. (2006). “Resistensi Insulin Pada Diabetes Melitus Tipe 2. Cermin Dunia Kedokteran, 150, 38-41.â€
  12. Nababan, Poltak. 2019. “Hubungan Kadar TNF-α Dengan HOMA-IR Pada Pasien Diabetes Mellitus Tipe-2 Di Rumah Sakit.†10(3): 580–83.
  13. Oroh, Wenda. 2018. “Hubungan Obesitas Dengan Kejadian Diabetes Melitus Di Wilayah Kerja Puskesmas Ranomut Kota Manado.†Jurnal Keperawatan 6(1): 1–6.
  14. Restyana, Fatimah. 2015. “Restyana Noor Fatimah.†Diabetes Melitus Tipe 2 4(5): 1–12. http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/1061.
  15. Sekaran et al. 2018. “Pemeriksaan Kadar HbA1c Pada Penderita Diabetes Mellitus Tipe 2 Yang Di Rawat Jalan Di Rsup h. Adam Malik Medan.†Pakistan Research Journal of Management Sciences 7(5): 1–2.
  16. Sianturi, David. 2021. “Korelasi Rasio Proinsulin / Insulin Dengan Reseptor Adiponektin Setelah Pemberian Ektrak Daun Puguntano (Curanga Fel-TerraeMerr.) Pada Tikus Putih Galur Wistar Model Diabetes Mellitus Tipe 2.†Jurnal Pembangunan Wilayah & Kota 1(3): 82–91.
  17. Soelistijo Sa, Hermina Novida, Rudijanto A, Soewondo P, Suastika K, Manaf A. 2015. Pengelolaan Dan Pencegahan Diabetes Melitus Tipe 2 Di Indonesia 2015.
  18. Suiraoka, I. P. 2012. “Penyakit Degeneratif. Yogyakarta Nuha Medika, 45-51.†: 45–51.
  19. Tsalissavrina, Iva, Kanthi Permaningtyas Tritisari, Dian Handayani, and Inggita Kusumastuty. 2018. “Hubungan Lama Terdiagnosa Diabetes Dan Kadar Glukosa Darah Dengan Fungsi Kognitif Penderita Diabetes Tipe 2 Di Jawa Timur.†Jurnal AcTion 3(1): 28–33.
  20. Utara, Universitas Sumatera. 2016. “Hubungan Resistensi Insulin Menggunakan Homa-Ir Dengan Rasio Profil Lipid Pada Penderita Sindroma Metabolik.†FAKULTAS KEDOKTERAN UNIVERSITAS SUMATRA UTARA