Peranan Kalsium dan Vitamin D Dalam Penanganan Osteoporosis, Pencegahan Fraktur Patologis, Serta Korelasi Terhadap Pandemi COVID-19
Abstrak
AbstractOsteoporosis remains a very significant public health problem, causing high morbidity and
mortality rates. Vitamin D deficiency (<50 nmol / L) is a worldwide epidemic with multiple
implications for human health. Inadequate serum 25-hydroxyvitamin D (25 (OH) D)
concentrations are associated with muscle weakness, decreased physical performance, and an
increased likelihood of falls and fractures. Various studies have shown that higher serum 25
(OH) D levels (at least 700 IU of vitamin D, especially cholecalciferol) will reduce the
incidence of fractures. The problem of osteoporosis has been exacerbated by the COVID-19
pandemic. As well known, COVID-19 is a respiratory tract infection caused by the new SARSCoV-2 virus. In general, this pandemic has caused deterioration of the economic and health
care systems in many countries. Under difficult circumstances, recent research has shown that
optimizing blood levels of vitamin D offers a solution that promises to reduce the risk of death
from COVID-19 infection. This literature review was aimed to discuss the role of calcium and
vitamin D in the management of osteoporosis, pathological fractures (brittle fractures), and
COVID-19.
Keywords: osteoporosis, vitamin D, COVID-19
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