COVID-19 In General
Abstrak
Abstract
The first time China reported a mysterious pneumonia that occurred on December 31, 2019 with an unknown cause, Coronavirus is an RNA virus strain, of the Coronaviridae family. Most Coronaviruses infect animals and circulate in animals. The incubation period for SARS-CoV- 2 ranges from 1 to 14 days. Presymptomatic or asymptomatic transmission during the incubation period plays an important role in the control of the COVID-19 pandemic. Worsening of clinical conditions occurs approximately 7 to 14 days after onset. It is known that COVID-19 infection in the lungs consists of three phases, namely: 1. The initial stage of inoculation and the beginning of disease formation; 2. The formation of lung disease, viral replication and local inflammation in the lungs; 3. This phase occurs when the inflammatory response of the host increases, even when the viral load begins to decrease, there is some organ damage where the lung is the main target organ of COVID-19, accompanied by several organ injuries as follows:: gallbladder, kidneys, and other organs. The criteria for the severity of COVID-19 consist of: asymptomatic or presymptomatic, mild, moderate, severe, and critical. Radiological images play an important role in diagnosis and provide guidance for treatment, the sensitivity of chest CT scans is greater than real-time polymerase chain reaction (RT-PCR) for diagnosis of COVID-19, and chest CT scans can be used to screen COVID-19 in patients. with symptoms but negative RT-PCR.
Keyword: Covid-19, RNA virus, Infection in the lung, Severity of covid-19
Referensi
Huang, C. et al. (2020) ‘Clinical features of patients infected with 2019 novel coronavirus in
Wuhan, China’, The Lancet, 395(10223), pp. 497–506. doi: 10.1016/S0140-6736(20)30183-5.
World Health Organization (2020) ‘World Health Organization;Novel Coronavirus (2019-nCoV)
Situation Report-1’, in. Available at: https://apps.who.int/iris/handle/10665/330760.
Wuhan virus outbreak: 15 medical workers infected, 1 in critical condition (2020) CNA.
Available at: https://www.channelnewsasia.com/news/asia/wuhan-pneumonia-outbreak-healthworkers-coronavirus-12294212 (Accessed: 27 October 2020).
Wang Qiang Wuhan University of Science and Technology, X. X. W. U. of S. and T. Z. Y. Z. H.
of W. U. C. S. W. U. of S. and T. Z. W. W. C. for D. C. and P. Z. Y. W. U. P. H. G. K. W. U. of
S. and T. W. M. W. U. P. H. L. G. W. C. for D. C. and P. C. W. Z. H. of W. U. J. X. W. C. for
D. C. and P. H. X. W. U. of S. and T. H. K. W. U. P. H. Z. N. W. U. P. H. (2019) Handbook of
-nCoV Pneumonia Control and Prevention. Hubei Science and Technology Press -
Penelusuran Google.
Deadly China Wuhan virus spreading human to human, officials confirm - Business Insider
(2020). Available at: https://www.businessinsider.com/deadly-china-wuhan-virus-spreadinghuman-to-human-officials-confirm-2020-1?r=US&IR=T (Accessed: 27 October 2020).
Fathiyah Isbaniah, Agus Dwi Susanto , Tjandra Yoga et al. (2020) PNEUMONIA COVID-19.
Perhimpunan Dokter Paru Indonesia Jakarta.
Shi, Y. et al. (2020) ‘An overview of COVID-19’, Journal of Zhejiang University-SCIENCE B,
(5), pp. 343–360. doi: 10.1631/jzus.B2000083.12 | H a l a m a n
Fehr, A. R. and Perlman, S. (2015) ‘Coronaviruses: an overview of their replication and
pathogenesis’, Methods in Molecular Biology (Clifton, N.J.), 1282, pp. 1–23. doi: 10.1007/978-
-4939-2438-7_1.
‘An update on the status of COVID-19: a comprehensive review’ (2020) European Review, 29
April. Available at: https://www.europeanreview.org/article/21046 (Accessed: 27 October
.
Romagnoli, S. et al. (2020) ‘SARS-CoV-2 and COVID-19: From the Bench to the Bedside’,
Physiological Reviews, 100(4), pp. 1455–1466. doi: 10.1152/physrev.00020.2020.
Siddiqi, H. K. and Mehra, M. R. (2020) ‘COVID-19 illness in native and immunosuppressed
states: A clinical–therapeutic staging proposal’, The Journal of Heart and Lung Transplantation,
(5), pp. 405–407. doi: 10.1016/j.healun.2020.03.012.
Clinical.Protocols.for.the.Diagnosis.and.Treatment.of.COVID-19.V7.pdf’ (no date). Available
at:
https://www.chinadaily.com.cn/pdf/2020/1.Clinical.Protocols.for.the.Diagnosis.and.Treatment.
of.COVID-19.V7.pdf (Accessed: 27 October 2020).
‘The viral, epidemiologic, clinical characteristics and potential therapy options for COVID-19: a
review’ (2020) European Review, 29 April. Available at:
https://www.europeanreview.org/article/21044 (Accessed: 27 October 2020).
‘Coronavirus disease 2019: a clinical review’ (2020) European Review, 29 April. Available at:
https://www.europeanreview.org/article/21045 (Accessed: 27 October 2020).
Singhal, T. (2020) ‘A Review of Coronavirus Disease-2019 (COVID-19)’, Indian Journal of
Pediatrics, 87(4), pp. 281–286. doi: 10.1007/s12098-020-03263-6.
Zhou, M., Zhang, X. and Qu, J. (2020) ‘Coronavirus disease 2019 (COVID-19): a clinical
update’, Frontiers of Medicine, pp. 1–10. doi: 10.1007/s11684-020-0767-8.
Guan, W. et al. (2020) ‘Clinical Characteristics of Coronavirus Disease 2019 in China’, New
England Journal of Medicine, 382(18), pp. 1708–1720. doi: 10.1056/NEJMoa2002032.
Song, F. et al. (2020) ‘Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia’, Radiology,
(1), pp. 210–217. doi: 10.1148/radiol.2020200274.
Coronavirus (COVID-19) (2020) National Institutes of Health (NIH). Available at:
https://www.nih.gov/coronavirus (Accessed: 27 October 2020).