Peritonitis et causa Apendisitis Akut Perforasi: Manifestasi Klinis, Pilihan Terapi Dan Pandangan Dalam Islam
DOI:
https://doi.org/10.30651/pc.v1i2.33111Kata Kunci:
peritonitis, apendisitis, perforasiAbstrak
Peritonitis akibat apendisitis akut perforasi merupakan kegawatdaruratan bedah kritis yang
secara signifikan meningkatkan morbiditas dan mortalitas pasien sekitar 5% karena risiko
komplikasi sepsis yang cepat. Tinjauan pustaka ini bertujuan untuk mengevaluasi secara
komprehensif etiologi, patofisiologi, manifestasi klinis, dan tatalaksana, serta integrasinya
dengan prinsip kesehatan dalam Islam. Metode yang digunakan berfokus pada studi ilmiah
terbaru yang diterbitkan dalam lima tahun terakhir di database seperti NCBI, Science Direct,
Scholar google untuk mencari evidence based medicine. Hasil temuan menunjukkan obstruksi
lumen memicu iskemia, nekrosis, hingga ruptur apendiks yang mencemari rongga peritoneum
dengan bakteri dan debris. Manifestasi klinis khasnya berkembang dari nyeri kuadran kanan
bawah menjadi nyeri tekan difus, rigiditas abdomen, demam, dan leukositosis berat.
Penanganan utama memerlukan tindakan source control segera melalui pembedahan yang
dikombinasikan dengan antibiotik empiris target bakteri Gram-negatif enterik dan anaerob,
seperti Seftriakson dan Metronidazol. Lebih lanjut, pandangan Islam memperkuat ikhtiar medis
ini melalui penekanan pada aspek kebersihan diri serta urgensi pengobatan tepat waktu.
Kesimpulannya, pengenalan dini gejala klinis dan intervensi multidisiplin yang cepat sangat
krusial untuk mencegah komplikasi sistemik yang fatal.
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