Aplikasi FT-IR ATR Spektroskopi untuk Identifikasi Parasetamol pada Jamu Sediaan Serbuk
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Abstrak
Parasetamol dengan rumus kimia N-(4-Hydroxyphenyl) acetamide adalah bahan kimia obat yang diduga ditambahkan secara illegal kedalam obat tradisional.  Metode analisis yang sederhana, cepat dan akurat diperlukan untuk pengendalian keberadaan bahan kimia obat yang ditambahkan pada obat tradisional. Identifikasi parasetamol dilakukan dengan mengunakan FTIR-ATR pada bilangan gelombang 650 to 2000 cm-1 dan profil yang dihasilkan dibandingkan dengan standar parasetamol. Hasil penelitian menunjukkan adanya serapan yang karakteristik pada standar parasetamol daerah finger print pada bilangan gelombang 1650 cm-1 yang menunjukkan C=O amida ulur; 1610 cm-1 (C=C aromatis ulur); 1650 cm-1 (N-H amida tekuk); 1500 cm-1 (C-H aromatis ulur) dan bilangan gelombang 830 cm-1 (=C-H aromatis ulur). Berdasarkan hasil analisis diperoleh bahwa tidak terdapat parasetamol pada sampel A dan sampel B dan terdapat parasetamol pada sampel C yang ditunjukkan dengan kemiripan profil  dengan parasetamol standar dan adanya gugus karakteristik yang menunjukkan parasetamol.Â
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Penulis
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