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Abstrak
Farmers in Indonesia are very dependent on pesticides to protect their crops from pests. Farmers are one of the subjects who are susceptible to pesticides and can cause disease due to pesticide accumulation. One of the disease that can arise due to exposure to pesticides is liver damage. This study wanted to determine the effect of pesticide exposure on liver damage seen from AST and ALT enzyme levels using farmer respondents in the Mojokerto area of 25 respondents. From the results of the study it was found that AST levels were influenced by age (P = 0.017), length of work (P = 0.035), and PPE usage (P = 0.044), while age, work period, length of work and usage of PPE did not significantly influence to ALT levels. It can be concluded that age, length of work and use of PPE affect AST levels. Therefore, to prevent the occurrence of pesticide poisoning, farmers must obey the rules on the use of pesticides such as using PPE regularly and always consuming healthy food.
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Referensi
- Desimal, Iwan. Mukono, Jojok. 2013. The Effects Of Organophosphate Pesticides Exposure To Liver Function And Cholinesterase Serum Activity Among Apple Growers Applying Pesticides. The Indonesian Journal of Public Health, Vol. 10 No. 1,p 70–76
- Direktorat Jendral Prasarana dan Sarana Direktorat Pupuk dan Pestisida Kementerian Pertanian 2011. Pedoman Pembinaan Penggunaan Pestisida
- EFLM (European Federation of Clinical Chemistry and Laboratory Medicine) Recommendation for Venous Blood Sampling, 2017
- Manfo, FPT., Mboe, S.A, Nantia, E.A, Ngoula, Ferdinand., Telefo, P.B., Moundipa P.F, and Fidelis Cho-Ngwa. 2020. Evaluation of the Effects of Agro Pesticides Use on Liver and Kidney Function in Farmers from Buea, Cameroon. Hindawi Journal of Toxicology Volume 2020, Article ID 2305764, 10 pages
- Misrha, Sankalp. 2012. Serum and Hepatocyte Enzyme. Journal Of Scientific & Innovative Research, Volume 1 Issue 3
- Peraturan Menteri Pertanian Republik Indonesia Nomor 39/Permentan/Sr.330/7/2015 Tentang Pendaftaran Pestisida
- Rehman, Tanzila., Hussain, Mazhar., Shad, M.A, Ghosh, Sirsendu., and Muhammad Aslam. 2017. Combined Effect of Age and Exposure on the Levels of Different Serum Enzymes in Workers of Pesticides Formulation Factories, Pakistan. Biochem Physiol, Vol 7(2): 238
- Rizvi, Farwa., Beg, Atif., Afzal, Muhammad and Abdul Majid Rajput. 2013. Association of Transaminase Levels with Obesity, Serum Lipids, Diabetes, Smoking and Level of Physical Activity. Journal of Islamabad Medical & Dental College (JIMDC):2(1):21-25
- Standard Operating Procedure for Collecting, Proccessing, and Storage of Blood Samples, 2017
- Tsani, R.A., Setiani, Onny., Dewanti, N.A.Y. 2017. Hubungan Riwayat Pajanan Pestisida Dengan Gangguan Fungsi Hati Pada Petani Di Desa Sumberejo Kecamatan Ngablak Kabupaten Magelang. JURNAL KESEHATAN MASYARAKAT (e-Journal) Volume 5, Nomor 3, Juli
- Lomanorek, V.Y., Youla A. Assa, Yanti M. Mewo. 2016. Gambaran Kadar Serum Serum Glutamic Oxaloacetic Transaminase (Sgot) Pada Perokok Aktif Usia > 40 Tahun. Jurnal e-Biomedik (eBm), Volume 4, Nomor 1, Januari-Juni 2016
- Widarti, Nurqaidah. 2019. Analisis Kadar Serum Glutamic Pyruvic Transaminase (SGPT) Dan Serum Glutamic Oxaloacetic Transaminase (SGOT) Pada Petani Yang Menggunakan Pestisida. Jurnal Media Analis Kesehatan, Vol. 10, No.1
- Wulandari, DD., Santoso, APR. 2020. Pengaruh Lama Paparan Pestisida Terhadap Aktivitas Kolinesterase, Serum Glutamic Oxaloacetic Transaminase (SGOT) Dan Serum Glutamic Pyruvic Transaminase (SGPT) Pada Pekerja Yang Terpapar Pestisida Golongan Organofosfat. Sains dan Terapan Kimia, Vol. 14, No. 1 (Januari 2020), 9-16
- Yuantari, M. G. C., Widianarko B., Sunoko, H. R. 2015. Analisis Risiko Pajanan Pestisida Terhadap Kesehatan Petani. KEMAS 10 (2) (2015) 239-245
Referensi
Desimal, Iwan. Mukono, Jojok. 2013. The Effects Of Organophosphate Pesticides Exposure To Liver Function And Cholinesterase Serum Activity Among Apple Growers Applying Pesticides. The Indonesian Journal of Public Health, Vol. 10 No. 1,p 70–76
Direktorat Jendral Prasarana dan Sarana Direktorat Pupuk dan Pestisida Kementerian Pertanian 2011. Pedoman Pembinaan Penggunaan Pestisida
EFLM (European Federation of Clinical Chemistry and Laboratory Medicine) Recommendation for Venous Blood Sampling, 2017
Manfo, FPT., Mboe, S.A, Nantia, E.A, Ngoula, Ferdinand., Telefo, P.B., Moundipa P.F, and Fidelis Cho-Ngwa. 2020. Evaluation of the Effects of Agro Pesticides Use on Liver and Kidney Function in Farmers from Buea, Cameroon. Hindawi Journal of Toxicology Volume 2020, Article ID 2305764, 10 pages
Misrha, Sankalp. 2012. Serum and Hepatocyte Enzyme. Journal Of Scientific & Innovative Research, Volume 1 Issue 3
Peraturan Menteri Pertanian Republik Indonesia Nomor 39/Permentan/Sr.330/7/2015 Tentang Pendaftaran Pestisida
Rehman, Tanzila., Hussain, Mazhar., Shad, M.A, Ghosh, Sirsendu., and Muhammad Aslam. 2017. Combined Effect of Age and Exposure on the Levels of Different Serum Enzymes in Workers of Pesticides Formulation Factories, Pakistan. Biochem Physiol, Vol 7(2): 238
Rizvi, Farwa., Beg, Atif., Afzal, Muhammad and Abdul Majid Rajput. 2013. Association of Transaminase Levels with Obesity, Serum Lipids, Diabetes, Smoking and Level of Physical Activity. Journal of Islamabad Medical & Dental College (JIMDC):2(1):21-25
Standard Operating Procedure for Collecting, Proccessing, and Storage of Blood Samples, 2017
Tsani, R.A., Setiani, Onny., Dewanti, N.A.Y. 2017. Hubungan Riwayat Pajanan Pestisida Dengan Gangguan Fungsi Hati Pada Petani Di Desa Sumberejo Kecamatan Ngablak Kabupaten Magelang. JURNAL KESEHATAN MASYARAKAT (e-Journal) Volume 5, Nomor 3, Juli
Lomanorek, V.Y., Youla A. Assa, Yanti M. Mewo. 2016. Gambaran Kadar Serum Serum Glutamic Oxaloacetic Transaminase (Sgot) Pada Perokok Aktif Usia > 40 Tahun. Jurnal e-Biomedik (eBm), Volume 4, Nomor 1, Januari-Juni 2016
Widarti, Nurqaidah. 2019. Analisis Kadar Serum Glutamic Pyruvic Transaminase (SGPT) Dan Serum Glutamic Oxaloacetic Transaminase (SGOT) Pada Petani Yang Menggunakan Pestisida. Jurnal Media Analis Kesehatan, Vol. 10, No.1
Wulandari, DD., Santoso, APR. 2020. Pengaruh Lama Paparan Pestisida Terhadap Aktivitas Kolinesterase, Serum Glutamic Oxaloacetic Transaminase (SGOT) Dan Serum Glutamic Pyruvic Transaminase (SGPT) Pada Pekerja Yang Terpapar Pestisida Golongan Organofosfat. Sains dan Terapan Kimia, Vol. 14, No. 1 (Januari 2020), 9-16
Yuantari, M. G. C., Widianarko B., Sunoko, H. R. 2015. Analisis Risiko Pajanan Pestisida Terhadap Kesehatan Petani. KEMAS 10 (2) (2015) 239-245